Clinical observation was made on 84 children with purpura who were admitted to the Pediatric Department of K-yungpook University Hospital during 10 year period from Jan. 1967 to Dec. 1976.
There were 51 boys and 33 girls and the results were as follows:
1. Leukemia was the most common cause of purpura, comprising 111.0%12"cases´, :oliowed by idiopathic thromboc,:toper-ic purpura 20.2´ (17 cases), meningococcemia 17. S% ;15 uasesj C allergic purpura 14.3% (12 cases) in order of decrea-ing frequency.
2. Tne highest incidence appeared to be between the ages of four and eight years, ar.J males (51 cases, were affected more frequently than females (33 cases).
3. The main c´.inical features in allergic purpura were abdominal pain, blood in stool, joint pain, and in meningococcemia, fever, vomiting & headache. In thrombocytopenic purpura (idiopathic thrombocytopenic purpura, leukemia, aplastic anemia and sepsis) anemia, fever C epistaxis were the main features.
4. Laboratory findings: hemoglobin value in children with leukemia and aplastic anemia was below 8.Ogm o and that of allergic purpura; meningococcemia and idiopathic thrombocytopenic purpura was normal or slightly decreased.
Normal or mild leukccytosis was noted in allergic purpura and idiopathic thrombocytopenic purpura: leukopenia in aplastic anemia: leukocytosis in meningococcemia and most of the leukemia.
The platelet count in thrombocytopenic purpura was usually below 100, 000/cu mm.
There were prolonged bleeding time, positive Rumpel-Leede test & normal coagulation time in most of the idiopathic thrombocytopenic purpura, and normal bleeding time, negative Rumpe: Leede test & normal coagulation time in most of the allergic purpura.
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